How MRI Works
On July 3, 1977, an event
took place that would forever alter the landscape
of modern medicine. Outside the medical research
community, this event made scarcely a ripple at
first. This event was the first MRI exam ever performed
on a human being.
It took almost five hours
to produce one image. The images were, by today's
standards, quite ugly. Dr. Raymond Damadian, a physician
and scientist, along with colleagues Dr. Larry Minkoff
and Dr. Michael Goldsmith, labored tirelessly for
seven long years to reach this point. They named
their original machine " Indomitable "
to capture the spirit of their struggle to do what
many said could not be done.
This machine is now in the
Smithsonian Institution. As late as 1982, there
were but a handful of MRI scanners
in the entire United States. Today there are thousands.
We can image in seconds what used to take hours.
The Basic Idea
If you have ever seen an MRI machine, you know that
the basic design used in most is a giant cube
. The cube in a typical system might be
7 feet tall by 7 feet wide by 10 feet long (2 m
by 2 m by 3 m), although new models are rapidly
shrinking. There is a horizontal tube
running through the magnet from
front to back. This tube is known as the bore
of the magnet. The patient, lying on his
or her back, slides into the bore on a special table.
Whether or not the patient goes in head first or
feet first, as well as how far in the magnet they
will go, is determined by the type of exam to be
performed. MRI scanners vary in size and shape,
and newer models have some degree of openness around
the sides, but the basic design is the same. Once
the body part to be scanned is in the exact center
or isocenter of the magnetic field,
the scan can begin.
In conjunction with radio
wave pulses of energy, the MRI scanner can pick
out a very small point inside
the patient's body and ask it, essentially, "What
type of tissue are you?" The point might be a cube
that is half a millimeter on each side. The MRI
system goes through the patient's body point by
point, building up a 2-D or 3-D map
of tissue types. It then integrates all of this
information together to create 2-D images
or 3-D models .
MRI provides an unparalleled
view inside the human body. The level of detail
we can see is extraordinary compared with any other
imaging modality. MRI is the method of choice for
the diagnosis of many types of
injuries and conditions because of the incredible
ability to tailor the exam to
the particular medical question being asked. By
changing exam parameters, the MRI system can cause
tissues in the body to take on different appearances.
This is very helpful to the radiologist (who reads
the MRI) in determining if something seen is normal
or not. We know that when we do "A," normal tissue
will look like "B" -- if it doesn't, there might
be an abnormality. MRI systems can also image flowing
blood in virtually any part of the body. This allows
us to perform studies that show the arterial
system in the body, but not the tissue
around it. In many cases, the MRI system can do
this without a contrast injection ,
which is required in vascular radiology.